Inflammaging, Explained
Inflammation often gets a bad name, but it is a vital part of your skin's natural defence system. It is how your skin responds to injury, irritation and threats from the outside world.
The problem starts when inflammation doesn't switch off. When low-level inflammation persists over months and years, scientists call it inflammaging, and it plays a quiet but significant role in how skin ages.
Two kinds of inflammation
Not all inflammation is the same. Beneath the surface, there are two very different types at work.
Acute inflammation is your skin's emergency response. It switches on when needed, such as after a cut or a burn, and then, ideally, switches back off once the job is done.
Inflammaging is low-level, persistent and often invisible. Rather than flaring up and settling down, it lingers in the background, quietly disrupting healthy skin function over time.
What inflammaging means for your skin
Inflammaging doesn't happen overnight. It builds in three stages.
1. Everyday triggers keep inflammation switched on
Modern life exposes skin to a steady stream of stressors: UV, pollution, stress and barrier disruption. Each one nudges the skin's defence system back on, so it never gets the chance to fully rest.
2. Inflammaging sets in
Over time, this becomes chronic, low-grade inflammation that never fully resolves. Along the way it generates oxidative stress: unstable molecules that damage healthy skin cells.
3. Key systems wear down
Gradually, three of the skin's most important systems begin to decline:
• Barrier function: skin holds less moisture and becomes more reactive
• Collagen integrity: firmness gradually declines
• Cellular renewal: skin renews itself more slowly
Don't just treat what you can see. Support how skin functions.
Because inflammaging works beneath the surface, tackling visible signs alone only goes so far. The more lasting approach is to support the systems that keep skin healthy in the first place.
That's the thinking behind Intuisse. Our formulas combine Active NAD+ with barrier-supporting lipids, peptides, ferments and targeted actives, working together to support the skin barrier, cellular function and overall skin resilience.
Your skin longevity routine
Three simple steps, each designed to support a different part of healthy skin function.
Step 1: Start with the microbiome
NAD+ Cleansing Lotion. A gentle daily toner and micellar water, designed to support the skin rather than strip it, so your routine begins without adding to the stress.
Shop the Cleansing Lotion
Step 2: Support cellular resilience
NAD+ Face Serum. A lightweight serum that supports collagen and elasticity for a brighter, more even complexion.
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Step 3: Strengthen the barrier
NAD+ Peptide Essential Cream. Active NAD+, peptides and squalane combine for deep hydration, firming and barrier support.
Shop the Essential Cream
Ready to support your skin from the inside out? Build your skin longevity rout