Intuisse Anti-Aging Skincare with NAD+ for Mature and Aging Skin

NAD+ (Nicotinamide Adenine Dinucleotide) is a vital coenzyme found in every living cell in our bodies. It plays an essential role in celullar energy production, DNA repair, managing cell death and longevity and to keep our cells functioning at their best.

- NAD+ drives energy production in the mitochondria - the cells 'powerhouse' - by converting nutriets from food into energy. It does this by helping to shift the energy produced in the Krebs Cycle into molecules of ATP (usable energy), ensuring cells have the fuel they need to perform.

- It also supports DNA repair enzymes such as PARPs, which help preserve genomic stability, and activates sirtuins, which are involved in stress responses, inflammation control, and epigenetic regulation.

By maintaining healthy NAD+ levels, these critical cellular processes can continue working efficiently, which contributes to resilience, repair, and overall healthy aging.

NAD+ levels decline naturally as we get older due to several interconnected processes in the body. Why?

- Higher consumption: NAD+-using enzymes increase in activity with age and inflammation, which means that more NAD+ is consumed on a daily basis while our body' ability to create new NAD+ also slows down.

- Lower recycling: At the same time, the body’s ability to recycle and restore NAD+ through the salvage pathway becomes less efficient with age.

- More DNA & oxidative stress: In addition, older cells are exposed to greater levels of oxidative and DNA damage, which activates NAD+-consuming repair enzymes even further.

Together, these factors create an imbalance where more NAD+ is being used up and less is being renewed, leading to an overall decline in NAD+ levels with age.

The most effective products for aging skin go beyond surface hydration and work at the cellular level to restore energy, repair damage, and rebuild firmness.

At Intuisse, two stand out:

Active NAD⁺ Face Serum: Powered by 5% pharma-grade NAD+, pomegranate enzymes, mediterranean marine plankton, meadowfoam seed oil, and fruit extracts. This combination stimulates cellular renewal, brightens uneven tone, protects against oxidative stress, and strengthens the skin barrier, leaving skin smoother, clearer, and more resilient.

Essential Cream: A deeply hydrating, restorative cream with Active NAD+, olive-derived squalane, natural peptides, and antioxidants. Together, they replenish moisture, support collagen and elastin, calm inflammation, and protect against pollution, improving firmness, elasticity, and radiance over time.

These products are designed to work synergistically, giving skin the energy, hydration, and protection it needs to look healthier and younger at every age.

Intuisse formulas are created to be safe and effective for all skin types. They are designed to work with your body's natural renewal functions, making them effective yet gentle.

However, because our products use powerful active ingredients that are highly potent, we recommend performing a patch test first if your skin is very sensitive or prone to reactions. For best guidance, consult with your dermatologist before use.

Skincare works in sync with your skin’s natural renewal cycle, which typically takes up to 28 days for complete turnover. That means lasting, visible results build over several weeks with with consistent AM/PM use.

Immediately/first few uses: Noticeable improvements in hydration, radiance and skin comfort.

10-14 days: Clinical studies show increased stimulation of collagen, laminin, and elastin, helping skin feel firmer and more resilient.

28 days: Visible improvements in texture, fine lines, and firmness as full skin cell turnover is achieved.

8–12 weeks: Results continue to strengthen, with enhanced elasticity, resilience, and a visibly healthier complexion.

Individual results vary based on skin type, routine consistency, lifestyle and sun protection.