Swiss Skin Tech: A Revolution in Skincare

Intuisse has partnered with Professor Giovanni Camici, PhD in cardiovascular physiology, Director of the Center for Molecular Cardiology at the University of Zurich and Laboratoire BIO-EC, a specialist French research centre for cosmetic and dermatological studies, to conduct extensive advanced experiments on the efficacy of our products.

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Increases the skin’s own production of laminin-V, elastin and collagen I in line with retinoic acid, without skin irritation or UV sensitivity

Source:

Laboratoire BIO-EC

Study description:

The aim of the study was to examine the impact of Intuisse’s 5% liposomal formulation on the following three bio-markers using human living skin explants ex vivo.

Laminin-V is a basement membrane glycoprotein and a key component of the anchoring complex connecting keratinocytes to the underlying dermis. Laminin-V contributes to the resistance of the epidermis against frictional stress but also to basement membrane regeneration and repair of damaged skin.

Elastin is a protein of the connective tissue responsible for the elastic properties of the skin. The principal function of elastin is its ability to elastically extend and contract in repetitive motion when hydrated.

Elastin is the major component (90%) of the elastic fibers of the skin. UV exposure is able to damage the elastic network of the dermis, including elastin.

Collagen I is the main component of collagen fibers. Collagen I levels decrease not only during the ageing process, but also in chronically sun-exposed human skin.

Conclusion:

Laminin-V:

After 10 days of treatment and compared to the untreated condition, the product Intuisse (5% NAD+-Liposomal formulation) induces a significant increase of laminin-V along the dermal-epidermal junction, by 106%**. In comparison, retinoic acid in the culture medium at 0.1 μM for 9 days induced only 68% increase.
** : p<0.01 (99%)

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Elastin:

After 10 days of treatment and compared to the untreated condition, Intuisse (5% NAD+-Liposomal formulation) induces a significant increase of elastin fibers in the papillary dermis, by 35%** (comparable to retinoic acid).
** : p<0.01 (99%)

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Collagen I:

After 10 days of treatment and compared to the untreated condition, Intuisse (5% NAD+-Liposomal formulation) induces a significant increase of type I collagen in the papillary dermis, by 15%** (comparable to retinoic acid).
** : p<0.01 (99%)

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Formulated for a high degree of naturality - no nasties

Source:

Naturalps SARL

Study description:

The International Organisation of Standardisation is an independent, non-governmental international organisation based in Geneva, Switzerland. ISO 16128 provides standardised guidelines on technical definitions and criteria for natural and organic cosmetic ingredients and products, which are reviewed every 5 years. An ingredient is considered of 'natural origin index’ if it contains more than 50% of natural raw sources (i.e. plants or minerals).

Conclusions:

Based on the evaluation of the ingredients, the Face Serum has a naturality score of 95.64%, the Essential Cream has a naturality score of 96.51%, the Eye Serum has a naturality score of 96.25%, and the Cleansing Lotion has a naturality score of 95.89%.

Need more proof? Download the app to see how our products score on Yuka: Face Serum (100/100). Essential Cream (100/100), Eye Serum (95/100), and Cleansing Lotion (100/100).

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Delivers a high degree of naturality as defined by ISO 16128, a standardised definition for natural cosmetics

Active NAD+ Essential Cream Conclusions:

After 28 Days,
volunteers reported
97% were satisfied with the product
97% found their skin softer
95% found their skin durably hydrated
89% found that their skin look had improved
89% of volunteers are convinced of the product efficiency
86% found their skin firmer, more tonic.

After 28 Days, Clinical Scoring (5pt scale) showed a change 1.71 to 3.51 or 105% improvement in hydration and a change from 1.86 to 3.63 or 95% improvement in skin smoothing.

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Active NAD+ Eye Serum Conclusions:

volunteers reported the following results:
85% of volunteers found that their skin is hydrated around the eyes
85% of volunteers felt an immediate feeling of comfort
82% of volunteers found that their skin is softer around the eyes
82% of volunteers are satisfied with the product
76% of volunteers found that their skin around the eye is softer

After 28 Days, Clinical Scoring (5pt scale) showed a change from 2.21 to 3.73 in skin hydration or 69% increase and from 2.52 to 3.79 in skin smoothing or 50% increase.

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