Active NAD+ Essential Cream- Advanced Skin Tightening & Anti-Wrinkle Formula

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Active NAD+ Essential Cream- Advanced Skin Tightening & Anti-Wrinkle Formula

Active NAD+ Essential Cream- Advanced Skin Tightening & Anti-Wrinkle Formula

Deeply hydrating and skin tightening face cream for wrinkles and dark circles enriched with peptides and squalane, powered by Active NAD+ to boost cellular renewal and restore radiance.

$100.00
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  • 14 days return policy
  • icon All replenishment subscriptions have a three month minimum

Formulated with our patented, high-absorption Active NAD+ combined with powerful antioxidant peptides and squalane, the Active NAD+ Essential Cream visibly reduces fine lines, eye wrinkles and dark circles, increases hydration, firms and tones skin texture while strengthening the skin-barrier.

Key benefits

After 10 days, significant increase in:

  • Collagen reducing wrinkles fine lines
  • Elastin tightening the skin’s texture
  • Laminin promoting the recovery of damaged cells

After 28 days:

  • 97% of users reported noticeably softer skin*
  • 95% of users experienced lasting skin hydration*
  • 89% of users found their skin appearance had improved*
  • 86% of users said their skin was firmer and more toned*
  • Dry skin reduced by more than 50%

With regular use, skin is significantly hydrated, dark spots are lightened and skin appears brighter

Scientific results

Purchase plans & refills

How to use

Apply gently to cleansed face and neck morning and evening. For optimal results, use after application of the Active NAD+ Face Serum

How to store

We recommend refrigerating (not freezing) your Intuisse products to maintain their pure, pharma-grade form. Once opened, our formulations have peak efficacy for two months at room temperature. Spare refills remain stable and potent for up to one year when refrigerated.

Ingredients

  • 5% pharma-grade Active NAD+ liposomal formulation
  • Olive-oil derived squalane
  • Natural peptides (99.4% natural origin ISO standard 16128)

Cold storage

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Customer Reviews

Based on 20 reviews
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87.5
I
Inessa Kogan
NAD cream

Absolutely love the product, perfect for daily use and great under the makeup.

J
Jenny Jones
Most hydrating skincare I’ve ever tried

Completely obsessed..this skincare line is a game changer

A
A.F.
Wonderful Results!

I've been using the Essential Cream more as an active hydrating serum - my skin became very sensitive as I reached my 60s, but this is both gentle on my skin and very effective. The Essential Cream has rejuvenated my skin! It improved my skin's overall appearance quickly, and the results just seem better over the three months I've been using it. I was worried because it has some fragrance, but it hasn't irritated my skin at all.

P
Paul Rocco Mirabella
Facial cream

Some of the finest skin care products I have used in several years
The active ingredients rejuvenate the skin and work wonders on the healing

L
Lara Buti
Amazing

The NAD formula has a visible effect on your face almost immediately,
I was amazed. I looked refreshed and more awake. I’m in my 40’s and loved all the intuisse products.

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Frequently Asked Questions

1. What is the Active NAD+ Essential Cream, and how does it benefit the skin?
Our Essential Cream is a daily moisturizer powered by 5% pure, pharma-grade liposomal NAD+, peptides, and olive-oil-derived squalane. NAD+ is a vital coenzyme found in every cell, essential for energy production, DNA repair, and cellular longevity. As levels naturally decline with age, skin becomes dull, less elastic, and slower to repair.

The Essential Cream:
  • Energises skin at the cellular level for resilience and repair.
  • Supports collagen and elasticity, smoothing fine lines.
  • Deeply hydrates and strengthens the skin barrier for healthier, brighter skin.

2. Is the Essential Cream effective for wrinkles and aging skin?
Yes, Intuisse’s NAD+ Essential Cream is specifically formulated to combat visible signs of aging. By replenishing NAD+, it revitalizes cellular function and stimulates collagen with peptides. The cream helps reduce fine lines, improve firmness, and refine texture. Visible improvements usually appear within 28 days of consistent AM/PM use.

3. How do I use and refill the Essential Cream?
Use:
Apply daily in the morning and evening, after cleansing (and serum). Smooth over face, neck, and décolletage. Always follow with SPF in the morning. Optimal results come with consistent use which supports ongoing skin renewal, visibly improves elasticity, and helps tighten sagging skin over time.

Refill:
  1. Twist the bottom part of the applicator and remove (& recycle) the empty refill.
  2. Remove the cap from the new refill and attach it to the top applicator pump.
  3. Reattach the bottom applicator bottle by twisting it to lock. Ready to be used again.
Each refill lasts 3–4 weeks. Keep your spare refills in the fridge for freshness and potency.

4. Is the Essential Cream suitable for all skin types?
The Essential Cream is formulated for all skin types. Since it contains potent actives like NAD+ and peptides, those with very sensitive or reactive skin should patch test first or consult a dermatologist.

5. Do I need to store the Essential Cream in the fridge?
You don't have to. Our formula is stable at room temperature for over 2 months. We recommend inserting one refill in the applicator and keeping it in your bathroom, while keeping the spare refills chilled for maximum NAD+ potency and extended shelf life (over 2 years). Chilled application also gives a soothing, de-puffing effect.

6. Is the Essential Cream clean & vegan?
The Active NAD+ Essential Cream is Vegan, non-GMO, and our formulas are up to 97% naturally derived. It contains a subtle fragrance with no allergens. Packaged sustainably with refillable applicators, recyclable refills, and FSC-certified cartons that are biodegradable and compostable.

7. At what age should I start using the Essential Cream?
You don’t need to wait for wrinkles to appear. NAD+ levels in the skin begin to decline from your 20s onward, which slows repair and accelerates aging. The Essential Cream can be used preventatively from your 20s or early 30s to maintain cellular energy and collagen levels — or later in life to target existing fine lines, dryness, and loss of firmness and elasticity.